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THE CREATINE
RESEARCH GUIDE
Why might creatine be beneficial to those with ALS?
Recent findings have suspected that the neuroprotective effects of creatine in the mouse model of ALS are due either to an increased availability of energy to injured nerve cells or to a blocking of the chemical pathway that leads to cell death.
I have ALS and I've been taking riluzole. Given that creatine has been reported to be more effective than riluzole in mice with ALS, should I switch my medication from riluzole to creatine?
Please keep in mind that, although the results of the studies are promising, the effectiveness of creatine in humans with ALS hasn't yet been tested (but see "clinical trials" below for information on upcoming trials). Also, riluzole and creatine may exert their neuroprotective effects by different mechanisms. Riluzole works by inhibiting the release of the neurotransmitter glutamate, which is thought to injure nerve cells in ALS through a mechanism known as "glutamate toxicity."
Creatine, on the other hand, may help cells that have already been damaged to keep going longer by providing the nerve cells with extra energy, or by preventing the damage from getting worse. Because the two compounds may work by slightly different mechanisms, researchers hope that they'll have an additive effect together. Until we know more about how these compounds work, please don't change your medication regimen without first discussing the matter with your physician.
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Creatine Facts And Articles
Creatine is, and always has been, a natural component of skeletal muscle. The only reason that creatine may seem like something new is a recent boom in scientific research in the area since the early 1990s. In a sense, creatine was rediscovered when world-class athletes became wise to the option of utilizing it to enhance their physical performance. Read More......
First and foremost creatine enhances physical performance by increasing the number of times that ATP can be recycled during physical exertion without increasing the absolute amount of ATP stored within our muscles. Read More......
First of all, of course you are going to gain weight if you are taking creatine and if you are taking it properly. Being an athlete, you should know muscle weighs more then fat. Also, are you taking the right amount of protein and water? Creatine is fine for women to take. The only downfall would be that some of us women may feel slightly bloated on it. Not a big deal to a serious athlete. Read More......
There have been hundreds of studies done on creatine that all show that it is a safe supplement. There are really very few side effects reported with creatine use but they include: upset stomach, muscle cramping, diarrhea and dehydration. Most of these side effects can be minimized by drinking plenty of water when taking creatine. In addition, people tend to have more side effects when taking the powder as opposed to a more direct delivery method like capsules and other ways. Read More......
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